Characteristics of Hematopoitic Growth Factor, G-CSF and Its Clinical Vision

Growth Factors G-CSF and GM-CSF: Clinical Options

The body's immediate response to bacterial infection becomes clinically evident as an inflammatory reaction accompanied by an acute-phase response in the liver and hyperthermia. Activation of the immune system must be counterregulated to curb these processes and to prevent (or at least minimize) damage to the host tissue. The major part of this intricate regulation is performed by the cytokine ...

Clinical applications of granulocyte colony stimulating factor (G-CSF).

G-CSF and GM-CSF in clinical trials.

Hematopoietic growth factors have now been purified, cloned, and produced in bacteria and yeast. Those that are currently in clinical study include erythropoietin, GM-CSF, G-CSF, M-CSF (also called CSF-1), and multi-CSF (also called interleukin 3). Growth factor appear likely to enhance the recovery and function of circulating white cells after standard-dose cancer therapy and high-bone-dose ca...

P-81: G-CSF Intrauterine and Thin Endometrium, and Pregnancy Outcome, Non Randomized Clinical Trial

Background Is G-CSF has any effects on cancelled ART cycle due to thin endometrium. This study showed the beneficial effects of G-CSF on thin endometrium. In two previous studies, some beneficial effects were reported and in another no effects were seen. MaterialsAndMethods In a nonrandomized clinical trial, fifteen cases were evaluated from June 2011 till September 2012. All cases had history ...

Treatment of Felty's syndrome with the haemopoietic growth factor granulocyte colony-stimulating factor (G-CSF).

Felty's syndrome (FS) (rheumatoid arthritis with neutropenia and splenomegaly) has a poor prognosis, largely because of the high risk of severe infection. Granulocyte colony-stimulating factor (G-CSF) is an emerging treatment for chronic neutropenia. We prospectively monitored its use in eight patients with recurrent infections or who required joint surgery. Significant side-effects were docume...